Interstitial keratitis following varicella vaccination.

V aricella is a highly transmissible disease caused by the varicella-zoster virus, with the most common manifestations being a maculopapular and/or vesicular rash accompanied by a fever. Current vaccination recommendations by the Advisory Committee on Immunization Practices include the administration of a vaccine for the prevention of varicella in children. Rare cases of ocular disease (sclerokeratouveitis and anterior uveitis) following varicella vaccination have been reported in the literature, associated with both the live attenuated Oka strain used in the vaccine and the wild-type virus. We report a case of avascular interstitial keratitis following the administration of the varicella vaccine. To our knowledge, this complication of the Oka strain vaccine has not been previously reported.